In the very near future, a deadly disease is ravaging the country. All citizens are required to submit to periodic blood tests and those testing positive are immediately taken off to a “Quarantine Center." In response, an underground railroad has sprung up to help those trying to escape the medical police and flee to Canada. In a rented cabin somewhere in the woods of the great American Northwest, Rae and Mags, friends since childhood, have become involved with escaping "runners" since Rae’s brother Gabriel (who was suffering from the disease in hiding) was turned into the government and taken away. They receive two visitors - Callie (in Act One) who has just broken out of a Quarantine Center and Val (in Act Two) who has tested positive but who has escaped the Medical Police before being taken away. These two visitors have unknowingly picked the wrong time to come by as the relationship between Mags and Rae is beginning to unravel. Rae, who is committed to continuing her involvement with runners even to her death, has just discovered that Mags has been sneaking away into a nearby town to seek the company of others. Caught, Mags confesses to wanting to give up their work in order to live a safer, more normal life. Rather than concentrating on helping their guests, Rae and Mags instead manipulate them in an attempt to sway each other into going along with their own desires. Just when you think you know what's going on, however, there is a devastating twist that will have you reconsidering all the assumptions that you have made about the situation and the main characters... This script was called "surprising and inventive" by Playwrights Horizons (NYC).